This work aims to highlight the problem of accidents in the construction industry.On the basis of collected and processed information the Flywheel Pulley accidents classification in the building is presented, depending on the building erection stage.The article gives a detailed description and analysis of such cases in the construction.The collecti
Thiophene based monoazo disperse dyes for polyester fabric
A series of monoazo disperse dyes have been prepared by coupling Coils 2-amino-3-carbethoxy-4,5-dimethylthiophene with various N-arylmaleimides.The monoazo disperse dyes were characterised by IR spectral studies and elemental analysis.These dyes were applied at 2 % depth on polyester fabrics and gave light yellow to brown colour hues with fair fast
On the hardness of quadratic unconstrained binary optimization problems
We use exact enumeration to characterize the solutions of quadratic unconstrained binary optimization problems of less than 21 variables in terms of their distributions of Hamming distances to close-by solutions.We also perform experiments with the Pokers D-Wave Advantage 5.1 quantum annealer, solving many instances of up to 170-variable, quadratic
CDK4/6 inhibitor-SHR6390 exerts potent antitumor activity in esophageal squamous cell carcinoma by inhibiting phosphorylated Rb and inducing G1 cell cycle arrest
Abstract Background Cell cycle dysregulation is common in human malignancies, and CDK4/6 inhibitors targeting cell cycle have potential antitumor activity.SHR6390 is a novel small molecule inhibitor specifically Slip-On targeting the CDK4/6 pathway.However, the role of SHR6390 in esophageal squamous cell carcinoma (ESCC) remains unknown, which will